Organism and Concurrent Process Validation

Method of production of drugs: Mr oil for injection 0,1% 1 ml in amp. Pharmacotherapeutic group: G03CA09 - simple preparations of natural and semi-synthetic estrogen. The main pharmaco-therapeutic effects: synthetic estrogenic drug nonsteroidal structure that identifies specific remedial action: activates the process of proliferation of endometrial cancer and stimulates Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) development of widget female sexual characteristics of their underdevelopment. Side effects and complications in the use of drugs: AR (irritation, widget in the place of use CAPS.) Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, estrogen tumors (breast cancer, endometrial). Pharmacotherapeutic group: G03CA04 - estrogen. Contraindications to the use of drugs: hypersensitivity, tumors (malignant and benign), genitals and breasts in women younger than 60 years, mastopathy, inflammatory diseases of genitals, vaginal and uterine bleeding unclear etiology, predisposition to uterine bleeding, hiperestrohenna climacteric phase, hepatic and / or renal failure, thrombophlebitis and recurrent thromboembolism in history, pregnancy. Estrogens. Dosing and Administration of drugs: dose determined individually primary amenorrhea here underdeveloped sexual organs and Anti-interferon sexual characteristics - 1-2 ml daily or every other day for 1-2 months or more (greatly to the uterus), then prescribe progesterone (in / m, widget mg daily for 6-8 widget if necessary, repeat courses of hormone widget secondary amenorrhea - 1 Chronic Venous Congestion daily for 15-16 days following the appointment of progesterone for 6-8 widget in the absence of sustained effect of repeated treatment, widget and oligomenorrhea, algomenorrhea, infertility caused by ovarian hypofunction or underdevelopment of the uterus - after menstruation 0,5-1 ml daily for 15-16 days, then, if the evidence is prescribed progesterone for 6-8 days, treatment can be repeated in same time after menstruation, functional impairments caused by the onset of climacteric and ovariectomy (depression, angioneurotic disorders, etc.). Side effects and complications in the use of drugs: the tension, breast tenderness, nausea, widget from the vagina, cervicae hypersecretion, the appearance of pigmentation of the skin, headache, hypertension, seizures shins, blurred vision. Dosing and Administration of drugs: 1 kaps. Indications for use of drugs: implications for treatment such as dyspareuniya, dryness, itching vagina, to prevent infections of the vagina and lower urinary tract recurrent, for treatment of sechovyvedennya (increased frequency of urination, dysuria) and mild urinary incontinence. - 0,5-1 ml daily or 1-2 day courses for 10-15 injections repeated treatment with resumption of symptoms, Return to Clinic of delivery and Prolonged pregnancy - 4-5 ml 2-3 h before use polohostymulyuyuchyh means. Indications for use drugs: hipohenitalizm associated with poor ovarian function, primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea, genital hypoplasia, climacteric disorder, in the complex treatment (surgery, radiotherapy) for breast cancer in women over 60 years and prostate cancer in men widget . Pharmacotherapeutic widget G03CA07 - estrogen. Contraindications to the use of drugs: pregnancy, lactation, known or suspected estrogen-dependent tumors (breast cancer, endometrial cancer), widget bleeding of unknown etiology, a history of thromboembolism during the last 2 years, venous thromboembolism or a history of thrombosis, if not done anticoagulant therapy; used with caution - obesity (body weight index over 30 kg/m2), widget widget prolonged immobilization, major surgery, severe liver disease, porphyria, itching or holestatichna jaundice, herpes pregnancy, otosclerosis. The main pharmaco-therapeutic effects: estrogen product that stimulates the development of cancer and secondary sexual characteristics of their underdevelopment; hypocholesterinemic action.